The IHS scores of HIF-1α in tumor tissue of mice between the group C+W and W, between the group W and C, and between the group C and M were different without statistical significance (H = 2.200, P = 1.000; H = 7.200, P = 0.201; and H = 1.800, P = 1.000, respectively). The gene discussed is HIF1A; the disease is neoplasm.