Furthermore, to explore whether CXCL13 can mediate long-term protection against primary tumors, 4T1-CXCL13-1 (n = 3) and 4T1-CXCL13-2 (n = 9) mice were rechallenged with parental 4T1 cells after over 6 months of complete tumor regression. This evidence concerns the gene CXCL13 and neoplasm.