Alzheimer's disease (AD) is a chronic neurodegenerative disorder that is well characterized by complex cellular and molecular alterations, such as loss of neurons and synapses, protuberant gliosis, dystrophic neuritis, formation of extracellular deposits of amyloid β (Aβ), and intracellular aggregated phosphorylated tau [1, 2]. This evidence concerns the gene MAPT and Alzheimer disease.