After 2 years of follow-up and, for two of them, without improvement despite immunosuppressive treatments, diagnoses of NDD were eventually retained: post-radiation encephalopathy, progressive supranuclear palsy (PSP), and Alzheimer's disease.<h4>Conclusion</h4>The presence of a high titer of anti-MAG antibodies may be found in NDD. This evidence concerns the gene MAG and Classical progressive supranuclear palsy.