There was a high protein expression of ANGPTL1, ANGPTL2, ANGPTL3, ANGPTL4, ANGPTL6, and ANGPTL8 in HCC cell lines (Figure 1 and Figure S1 A-G), indicating that ANGPTLs may play a vital function in HCC. The gene discussed is ANGPTL6; the disease is hepatocellular carcinoma.