Moreover, MM-derived exosomes contain and thus increase the levels of microRNA-146a in BMSCs, leading to enhanced secretion of several cytokines and chemokines by BMSCs, including CXCL1, IL6, IL-8, IP-10, also known as CXCL10, MCP-1, and CCL-5, resulting in enhanced MM cell viability and migration (145). This evidence concerns the gene CCL5 and Miyoshi myopathy.