Xiao and colleagues reported that linc00265 facilitated cell angiogenesis via sponging miR-382-5p, leading to upregulation of Spermidine/spermine acetyltransferase-1 (SAT1) and vavguanine nucleotide exchange factor 3 (VAV3) in osteosarcoma, which caused suppression of proliferation, motility and angiogenesis in osteosarcoma cells (33). Here, VAV3 is linked to osteosarcoma.