USP7 and colorectal carcinoma: Studies have demonstrated that linc00265 downregulation blocked colorectal cancer (CRC) oncogenesis via enhancement of zinc finger MIZ-type containing 2 (ZMIZ2) expression due to sponging several miRNAs, including miR-375, miR-30c-2-3p, miR-324-3p and miR-130-3p, leading to upregulation of ubiquitin specific peptidase 7 (USP7) and stabilization of β-catenin (19).