The intraoperative peritoneal lavage fluid CEA, CA125, and IL-6 in peritoneal metastasis group were higher than those in other metastasis groups and nonmetastasis groups (P < 0.05); there was no significant difference in the intraoperative peritoneal lavage fluid CA19-9, IL-4, and IL-2 levels among peritoneal metastasis group, other metastasis groups, and nonmetastasis groups (P > 0.05). This evidence concerns the gene IL6 and metastasis.