METTL16 and neoplasm: The genes IGF2BP1, IGF2BP3, and YTHDF1 were significantly upregulated in tumor samples, whereas the genes YTHDC1, YTHDC2, ALKBH5, METTL14, METTL16, FTO, WTAP, YTHDF2, YTHDF3, and RBM15B were significantly downregulated in tumor tissues (Figure 1(c)).