On univariate Cox analysis, higher of age, Ps-AF, LAD, Gal-3, and ALD were associated with AF recurrence, whereas in multivariate analysis, only Gal-3 (HR = 1.28, 95% CI: 1.04-1.56, p = 0.02) and ALD (OR = 1.02, 95% CI: 1.00-1.03, p < 0.03) remained significantly associated with AF recurrence after RFCA (Table 2). The gene discussed is LGALS3; the disease is atrial fibrillation.