KEGG pathway enrichment analysis showed that cell cycle (p value = 5.85E − 08), viral carcinogenesis (p value = 6.93E − 06), ECM-receptor interaction (p value = 5.00E − 05), PI3K-Akt signaling pathway (p value = 0.001557342), and pathways in cancer (p value = 0.011811389) were five significantly enriched pathways in luminal A breast cancer. This evidence concerns the gene AKT1 and cancer.