The univariate odds ratios for severe/necrotizing AP were 6.08 (1.77–20.81) and 2.90 (1.19–7.05) per 1-loge[mg/l] increase in sCD206 and 9.33 (1.05–82.81) and 3.34 (1.04–10.67) per 1-loge[%] increase in vWF:Ag, in the prospective cohort and in the ICU cohort, respectively. Here, RENBP is linked to alkaline phosphatase measurement.