MYCN and neuroblastoma: In Neuroblastoma, T-cells, CD8+ T cells, Th17, NKT cells, Th1 cells, Treg cells, and DCs were significantly higher enriched in the high risk NBL without MYCN amplification group compared to high risk NBL with MYCN amplification (p < 0.05), TFH was high in the 3 subgroups and showed significant positive association with survival in the high risk NBL without MYCN amplification group.