GLP1R and type 2 diabetes mellitus: In patients with T2DM and DKD with a GFR of 15-30 mL/min/1.73 m2 , and HbA1c above target, DPP-4 inhibitors, some sulfonylureas (glipizide and gliclazide) and GLP-1 RA MAY BE CONSIDERED to improve glycemic control.