Generally, GBM can be classified into three genetic profiles: proneural/neural, classical, and mesenchymal, correlating to changes in the gene expression patterns of platelet-derived growth factor receptor alpha (PDGFRA)/IDH1, EGFR, and neurofibromatosis type 1 (NF1), respectively [27, 28]. This evidence concerns the gene EGFR and glioblastoma.