F2R and concussion: In addition, PAR1 protein levels were significantly increased in the mTBI + FEAM group one day following trauma compared to control (1.79 ± 0.23, 1.00 ± 0.05 fold-increased, respectively, p = 0.003, Fig. 8E) and in mTBI group 30 and 104 days p-mTBI compared to control (Day 30: 1.41 ± 0.11, 1.00 ± 0.13 fold-increased, respectively, p = 0.05, Day 104: 1.7 ± 0.1, 1.00 ± 0.09 fold-increased, respectively, p = 0.001, Fig. 8E).