BNIP3 and rheumatoid arthritis: Inhibition of BNIP3 expression was associated with decreased cell proliferation (Fig. 5A–D) and enhanced apoptosis (Fig. 5E–H), and was closely related to the reduction of mitophagy caused by the inhibition of BNIP3 in RA-FLSs under hypoxia (Fig. 6A–C).