Inflammatory cytokines previously shown to be mildly upregulated in ALS blood include CCL5 (RANTES), TGF-β1, IL-1β and IL-6, while IL-23, IL-8, TNF-α and its soluble receptors were moderately upregulated [30–36]. The gene discussed is CXCL8; the disease is amyotrophic lateral sclerosis.