These included pro-inflammatory cytokines within our CBA panel (IL-6, IL-8, MCP-1, IP-10, RANTES, ICAM-1 and VCAM-1), and factors not in our cytokine CBA panel but implicated in ALS (MMP9, angiogenin, angiopoietin-2, VEGF, uPAR) [44–47]. This evidence concerns the gene MMP9 and amyotrophic lateral sclerosis.