To identify potential factors accounting for promotion of tumor growth by α-SMA<sup>high</sup> CAFs, nCounter PanCancer Immune Profiling Panel (NanoString) was used.<h4>Results</h4>In luminal breast cancer, presence of intratumoral CAFs expressing high level of α-SMA (13% of lumBC group) correlated with poor prognosis (p = 0.019). The gene discussed is ACTA1; the disease is neoplasm.