Similarly, KEGG results enriched for many pathways known to be associated with cardiovascular disease (Table 4, Fig. 4C&D), such as cardiomyopathy (Fig. 5A), cAMP signaling pathway (Fig. 5B), cytokine-cytokine receptor interaction (Fig. 5C), apoptosis (Fig. 5D), MAPK signaling pathway (Figure S3A), HIF-1 signaling pathway (Figure S3B), calcium signaling pathway (Figure S3C), and NF-kappa B signaling pathway (Figure S3D). The gene discussed is HIF1A; the disease is cardiomyopathy.