BRAF and melanoma: Initial approval of the FoundationOne CDx, received 30 November 2017, included two named products indicated for BRAF V600E melanoma, Tafinalar (dabrafenib) and Zelboraf (vemurafenib) for BRAF V600E, and two named products, Mekinisth (trametinib) or Cotellic (cobimetrinib) in combination with Zelboraf.