AIF1 and neoplasm: We show that the increase of p-IGF1R expression in tumoral lung tissues correlated with proliferation (Ki67), macrophage (Iba1) and tumor-associated macrophage, TAMs (CD68) presence (Pearson ́s correlation coefficient, r = 0.5906, p = 0.0013; r = 0.4012, p = 0.015; and r = 0.6257, p = 0.0341, respectively) (Fig. 1B).