Examination of other models including TACSTD1 KO and TACSTD2/TACSTD1 double KO cells and thorough inspection of lungs of Tacstd2 KO mice (and possibly GDLD patients) is thus needed to clarify the exact role of Trop2 in formation of lung epithelial barrier. Here, TACSTD2 is linked to gelatinous drop-like corneal dystrophy.