NF1 and cutaneous melanoma: Cutaneous melanoma in western population is classified into 4 molecular subtypes based on the pattern of the most significantly mutated genes, namely mutant BRAF (52%, 166/318), mutant RAS (28%, 88/318), mutant NF1 (14%, 46/318), and Triple-WT (wild-type) (14%, 46/318)1.