For example, miR-375, miR-27a, and miR-26b can inhibit the transcription of SLC7A11 mRNA [118–120]; miR-182–5p and miR-378a-3p negatively regulate the expression of GPX4 and SLC7A11 by directly binding the 3' UTR of GPX4 and SLC7A11 mRNA [121]; and miR-137 directly targets glutamine transport SLC1A5 to regulate ferroptosis negatively in melanoma cells [122]. This evidence concerns the gene GPX4 and melanoma.