Prohibitin has been termed an oncogene, as it promotes proliferation and dedifferentiation in neuroblast cells (MacArthur et al, 2019) and a tumour suppressor gene beacuse it was shown to inhibit the cell cycle by repressing E2F-regulated genes via recruitment of the retinoblastoma protein and histone deacetylases (Wang et al, 2002). The gene discussed is PHB1; the disease is neoplasm.