TREM2 and neoplasm: Furthermore, Macro-1 displayed a population-specific gene expression pattern of tumor-associated macrophage markers, such as TREM2, FABP5, and FABP4 (Figures 2B and 2C).44, 45, 46 Macro-2 expressed high levels of neutrophil-attracting chemokines, including CXCL2, CXCL3, and CXCL8.47 In addition, this population exhibited high expression of GPR183, DUSP2, CD83, and HLA class II genes (Figures 2B and 2C).