Furthermore, Macro-1 displayed a population-specific gene expression pattern of tumor-associated macrophage markers, such as TREM2, FABP5, and FABP4 (Figures 2B and 2C).44, 45, 46 Macro-2 expressed high levels of neutrophil-attracting chemokines, including CXCL2, CXCL3, and CXCL8.47 In addition, this population exhibited high expression of GPR183, DUSP2, CD83, and HLA class II genes (Figures 2B and 2C). Here, CXCL8 is linked to neoplasm.