Interestingly, compared to the healthy individuals, significantly higher serum VEGF-C levels could be detected not only in ovarian cancer patients with high pT-stage (mean values 4258.89 pg/mL vs 7236.02 pg/mL, p<0.001, Fig 2B), but also in ovarian cancer patients with low pT-stage (mean values 4258.89 pg/mL vs 7361.09 pg/mL, p = 0.023, Fig 2B). Here, VEGFC is linked to ovarian cancer.