Also, IP activated BCL-ALL oncogenic marker (AML1, c-Myc, ETV6, and Ikarose1) expression at the protein level (Fig. 3A) However, IP-induced AHR, cell proliferation, and oncogenic marker activation of BCL-ALL was abrogated in AHR-silenced cells compared to the findings in mock-infected cells (Fig. 3A). This evidence concerns the gene RUNX1 and acute lymphoblastic leukemia.