E2F1 and leukemia: First, we analyzed the expression patterns of proliferation-related genes (cyclin D1, E2F1, and Ki-67), stem cell-like (OCT4, Nanog, and SOX2), and leukemia-associated mutant markers (AML1, ETV6, and Ikaros1) in BCP-ALL cells (REH and Nalm-6) treated with IP to explore the potential functional relationship between IP and BCP-ALL.