Mechanism notwithstanding, repression of LINC00111 by TBX2-CoREST appears to be important for breast cancer proliferation and survival; analysis of the METABRIC dataset also indicates that breast cancer patients with LINC00111-over-expressing tumours have markedly better overall survival at months 120–240 of the study, compared to tumours in which LINC00111 is downregulated (Supplementary Figure S11). This evidence concerns the gene TBX2 and breast carcinoma.