Among them, HGBL-DH was the most common, with 3 cases of MYC/Bcl-2 HGBL-DH (8.6%, including 2 cases complicated with follicular lymphoma) and 21 cases of MYC/Bcl-6 HGBL-DH (60.0%, including 1 case complicated with the hemophagocytic syndrome). This evidence concerns the gene BCL6 and hemophagocytic syndrome.