In terms of viral infection, it was demonstrated that the presence of innate lymphocyte cells (ILC), a type of immune cell that shares many characteristics of the CD4+ T helper cell but without adaptive immunity receptors/lymphoid lineage expression, can induce the production of IL-13 (53, 54) when it presents the Th2 profile (called ILC2) in the respiratory tract. The gene discussed is CD4; the disease is viral infectious disease.