Although elevations in the plasma levels of both IL-13 and IL-17, among other cytokines, were observed in symptomatic patients infected by SARS-CoV-2 as compared to controls (51), higher IL-13 levels in saliva of COVID-19 patients presenting SIgA than COVID-19 patients without SIgA or control with SIgA has not been reported before. This evidence concerns the gene IL17A and COVID-19.