It is noteworthy to point out that regardless of the type of interferons [type-I (IFN-α and IFN-β); type II (IFN-γ); or type-III (IFN-λ)], in a viral infection, these molecules are the main antiviral cytokines that promote the infection control and the ability to elicit an adaptive immune response to improve the viral clearance (70). Here, IFNG is linked to infection.