Taking our findings together, we were able to reinforce the importance of IL-17 in the immune response of airways’ mucosa and show, for the first time, relevant characteristics and associations between cytokines in COVID-19 groups, two months after the SARS-CoV-2 infection, in producers or non-producers of salivary specific-SIgA for SARS-CoV-2 virus. This evidence concerns the gene IL17A and COVID-19.