It was found a significant decrease in the IL-12p70/IL-10 ratio (Figure 3B) between the control group without SIgA and the control group with SIgA, as well as in the IFN-γ/IL-10 ratio (Figure 3G) between the control group without SIgA, the control group with SIgA, and the COVID-19 group with SIgA. The gene discussed is IFNG; the disease is COVID-19.