ERH and hepatocellular carcinoma: To verify whether SMPDL3A affected the proliferation of HCC cells by regulating ERH, a Huh7 cell line overexpressing SMPDL3A (SMPDL3A cells) and another Huh7 cell line overexpressing SMPDL3A with knockdown of ERH (SMPDL3A-shERH cells) were established.