AKT1 and cancer: The results showed that the KEGG pathways were mainly focused on the PI3K-Akt signaling pathway, focal adhesion, proteoglycans in cancer, regulation of actin cytoskeleton, axon guidance, ribosome, phagosome, osteoclast differentiation, platelet activation, and extracellular matrix–receptor interaction (adjusted P < 0.05; Figure 5B).