In another study, a compound heterozygous mutation in the POLR1C gene in childhood ataxia with leukodystrophy with a missense mutation (c.713A > G: p.Asp238Gly) frameshift mutation (c.698_699insAA: p.Tyr233fs) was reported by Han et al. (11). This evidence concerns the gene POLR1C and Ataxia.