On the basis of network topology algorithm, all core target genes in VA against As-linked dermatitis were reported, including JUN, TP53, MAPK3, MAPK1, MAPK14, IL6, AKT1, STAT1, FOS, ESR1, TNF, CREB1, IL10, IL2, SP1, CASP3, CDKN1A, IL4, EGFR, IL1B, MCL1, BCL2, CXCL8, TGFB1, IFNG, BCL2L1, NOS2, CCL2, and VEGFA (Figure 2). The gene discussed is IFNG; the disease is skin disorder.