KRAS and gastric cancer: The present study also constructed the DEcircRNA-DEmiRNA-hub gene subnetwork including 22 pairs of the upcircRNA-downmiRNA-upmRNA network, and it was found that 5 hub genes consisting of TFDP1, KRAS, LMNB1, MET, and MYBL2 revealed a high expression level in GC tissue samples compared with adjacent tumor-free gastric tissue samples.