As STIM1 and STIM2 differ in their expression profiles (at least in T cells) and the ER Ca2+ concentration to which they respond (Shaw and Feske, 2012), this could potentially explain why only one of them, STIM2, showed a change in expression between CHL and other B cell lymphomas. The gene discussed is STIM2; the disease is B-cell non-Hodgkin lymphoma.