STAT3 and lung cancer: The antitumor effects of curcumin have also been associated to inhibition of Signal Transducer And Activator Of Transcription 3 (STAT3) - which is implicated in sustaining proliferation—resulting in downregulation of cyclin B1 and consequently in G2/M phase arrest in lung cancer cells (Wan Mohd Tajuddin et al., 2019).