VEGFA and macular retinal edema: A systematic review article (n = 1631, 8 RCTs, moderate certainty evidence) showed that anti-VEGF drugs were more effective in improving visual acuity and reducing macular edema in patients with branch retinal vein occlusion than placebo, laser photocoagulation, and local ocular injection of glucocorticoids (Shalchi et al., 2020).