AKT1 and malignant colon neoplasm: EMT mechanistically was studied in some cancers such as breast (Shan et al., 2015; Yang et al., 2019), thyroid (Lin et al., 2018), and colon cancer (Ma et al., 2019), and related signaling pathways were found PI3K/AKT/PKB, MAPK/ERK (Ma et al., 2019; Yang et al., 2019), WNT/β-catenin (Shan et al., 2015), and NF-κB (Lin et al., 2018) pathways.