Studies have shown that adiposity, insulin resistance, and hyperglycemia can induce systemic inflammation through stimulating the production of proinflammatory proteins such as C-reactive protein and cytokines including interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) [7]. The gene discussed is CRP; the disease is Insulin resistance.