MSH2 and bladder transitional cell carcinoma: Figure 3A shows that high KIF2C expression was significantly correlated with TMB of 24 tumors, and only significantly negatively correlated with THYM. Figure 3B shows that high expression of KIF2C was positively correlated with MSI in BLCA, COAD, HNSC, LIHC, LUSC, SARC, STAD, UCEC, and UCS. dMMR can induce MSI production, so we evaluated the association between the expression level of KIF2C and the mutation levels of five MMR genes (MLH1, MSH2, MSH6, PMS2, and EPCAM). Figure 3C shows that KIF2C was significantly associated with MMR genes in 30 tumors.