EXT1 and neoplasm: Figure 11 shows that KIF2C interacts with genes such as CENPH, ADAM9, NDEL1, and EXT1 and is associated with biological functions such as tubulin binding, sister chromatid segregation, and MHC II antigen presentation, suggesting that KIF2C is involved in cell cycle and immune regulation. In addition, previous studies found that the KIF2C-related CENPH, EXT1, can promote tumor progression (Wu et al., 2015; Lu et al., 2017; Kong et al., 2021) and ADAM9 has a significant role in tumor growth, metastasis, and immune evasion (Chou et al., 2020).