STK11 and Peutz-Jeghers syndrome: Due to STK11 role as a tumor suppressor, patients with PJS also possess a significant risk for developing an array of malignancies including colorectal, breast, gastric, small bowel, pancreatic, ovarian, cervical, lung, thyroid, and gonadal tumors (McGarrity et al., 2001; Syngal et al., 2015).