CRP and insomnia measurement: The association was modestly attenuated after further adjustments for higher educational level, insomnia, fed-up feelings, LDL cholesterol, C-reactive protein, and eGFR, but remained significant (β coefficient=0·072; 95% CI 0·041–0·104, p=7·7 × 10–6), equivalent to 3·1 years (95% CI 1·8–4·5) of age-related change in LTL (final model; appendix p 25).