ACKR3 and neoplasm: According to the previous research, eight genes including CXCR4 (C-X-C Motif Chemokine Receptor 4) [15], CXCR7 (C-X-C Motif Chemokine Receptor 7) [16], CDH2 (Cadherin 2) [17], ITGB3 [18], ANXA2 [19], CD44 [9], CTGF [9] and ITGA2 [18] were proved to exert pivotal role in mediating the colonization of the disseminated tumours, which were applied to investigate the correlation between DEGs and the adhesion.