Currently, several biomarkers, such as C-reactive protein (CRP), which is characterized as a inflammatory marker, and procalcitonin (PCT), which serves as a marker of bacteremia, have been widely utilized as acute phase reactants in critically ill patients, yet their diagnostic and prognostic performance for sepsis are suboptimal (Henriquez-Camacho and Losa, 2014). The gene discussed is CRP; the disease is bacterial infectious disease with sepsis.