Compared with the control (iron-deficiency treatment for 0 minutes), HA3 or HA4 generally showed only 1- to 2-fold expression in both ZQ and TO (Supplementary Data Fig. S2a, b, d, and e), whereas HA6 showed 2000- to 3000-fold expression in ZQ (Supplementary Data Fig. S2f) but only 0- to 100-fold expression in TO (Supplementary Data Fig. S2c) under iron-deficiency treatment for 15, 30, and 60 minutes. This evidence concerns the gene KRT36 and Iron deficiency anemia.