Furthermore, agents known to inhibit platelet activation and aggregation by targeting ADP, cyclooxygenase-1, and glycoprotein IIb/IIIa receptors in cerebral ischemic attack, idiopathic intracranial hypertension, cerebral venous thrombosis, and acute coronary syndromes include ticlopidine, clopidogrel, aspirin, and tirofiban [43,44,45]. This evidence concerns the gene PTGS1 and acute coronary syndrome.