Other glycosidases involved in lysosomal storage disorders include α-mannosidase (EC 3.2.1.24), β-mannosidase (EC 3.2.1.25), α-L-fucosidase (EC 3.2.1.51), trehalase (EC 3.2.1.28), and β-glucuronidase (EC 3.2.1.31), whose malfunction cause, respectively, mannosidoses [45,46,47], fucosidosis [48,49], trehalase deficiency [50,51] and Sly disease [52]. The gene discussed is TREH; the disease is hyperinsulinemic hypoglycemia, familial, 4.